LONDON -- He ran. He threw. He conquered. Colin Kaepernick did it all Sunday, rushing for two touchdowns and throwing for another to lead the San Francisco 49ers to their fifth straight victory, 42-10 over the winless Jacksonville Jaguars at Wembley Stadium. "The offensive line did a great job, made it easy for me," said Kaepernick, who led the 49ers to the Super Bowl last year. "I think this is one of the first game that we started that fast." Kaepernick ended up with 164 yards passing and 54 yards rushing, Frank Gore also ran for two scores and 71 yards, while Kendall Hunter rushed for 84 yards for the 49ers (6-2). But it was Kaepernick that made the key plays by when the team needed it early. "He looked much like a running back, and thats great courage," 49ers coach Jim Harbaugh said. "You dont always see that in the quarterback position. As soon as he saw that window, he had a great dart and speed to get the ball into the end zone." The Jaguars (0-8) were the "home" team at Londons iconic soccer venue, playing in the British capital for the first of their four-year run of regular-season NFL games in London. They had plenty of fan support, too, with many of the 83,559 spectators waving their giveaway Jaguars flags throughout the evening. None of that affected what was happening on the field, and on the field it wasnt pretty for the Jags. "Our seasons not over," Jaguars receiver Justin Blackmon. "Were not going to just go out there and get our (butts) kicked, were going to go back out there and fight." Kaepernick made his first big play on San Franciscos first possession, quickly throwing to fullback Bruce Miller on the right sideline for a 43-yard gain. A few plays later, Kaepernick scrambled for 4 1/2 yards on a third-and 5, setting up Gore for a short gain and a first down. After an incomplete pass, Gore ran 19 yards for the first touchdown. Kaepernick took over the scoring after that, running 13 yards and diving into the corner for the second touchdown late in the first quarter, then passing to Vernon Davis in the corner of the end zone for another, and finally holding it and scrambling for 7 yards and a touchdown. And all in the first half. "Kaepernick is a stud athlete and he showed it again tonight," Jaguars linebacker Paul Posluszny said. Besides a 38-yard field goal by Josh Scobee in the waning seconds of the half to make it 28-3, Jacksonville had little to be happy about. But the 49ers fumbled in their own territory late in the third quarter, giving the Jaguars their best chance to score. They took it as Chad Henne tossed a 29-yard touchdown pass to Mike Brown to make it 28-10 with 3:00 to go. The Niners bounced right back, first with Kyle Williams returning the kick 47 yards before getting pushed out of bounds. Hunter ran 41 yards on the next play, bringing the ball to the Jacksonville 13. Gore then ran for 9 yards, 2 yards and the final 2 on three straight plays for the touchdown. San Francisco linebacker Dan Skuta scored the final points, recovering a fumble and running it back 47 yards for a touchdown after Marcedes Lewis let the ball loose following a 6-yard completion from Henne. "There are definitely some plays that we needed to make, and the red zone really killed us," Henne said. "If its just players needing to make plays, we have to make them. We need to man up." Both teams have a bye next week, as is usual after the trip to London. The Jags then visit Tennessee on Nov. 10 while the 49ers host Carolina. "The bye week is coming at a good time," Jaguars coach Gus Bradley said. "We can take the time to evaluate where were at with our whole team and recommit to take the next step." Sundays encounter was the eighth regular-season NFL game at Wembley, the home of Englands national soccer team, and the second this year. The Minnesota Vikings beat the Pittsburgh Steelers 34-27 last month. Next year, there will be three games in London. The Jaguars will face the Dallas Cowboys in their second game of the four-game stretch, while the Detroit Lions will play the Atlanta Falcons and the Miami Dolphins will take on the Oakland Raiders. Harbaugh seemed to love the experience of making the trip, likening it to another huge sporting event. "The beginning of the game when they were playing the two national anthems, I felt like I was at the Olympics," Harbaugh said. "As a youngster, I always wanted to be in the Olympics and at that moment I was feeling like the moment when they play the gold medal and the silver medal and the bronze medal, the different anthems. "I got a chill when the gal was singing God Save the Queen." NOTES: R&B artist Ne-Yo sang "The Star-Spangled Banner" and Laura Wright sang "God Save the Queen." ... Former San Francisco quarterback Joe Montana and receiver Dwight Clark were the honorary captains for the 49ers. ... It was San Franciscos second game at Wembley. The Niners beat the Denver Broncos 24-16 in 2010. Jason Pominville Jersey . It certainly isnt a coincidence that Dwight Howard has scored at least 20 points in each game of the winning streak. Gilbert Perreault Jersey . - Loosening up for their first training camp practice, the Miami Dolphins high-stepped sideways up and down the field while House of Pains song "Jump Around" blared on the loudspeakers. http://www.officialsabresfanstore.com/au...-sabres-jersey/. - A retired Indiana school principal who was NASCAR star Jeff Gordons drivers education teacher was killed with his wife in a Tennessee crash while returning from watching Gordon race. Rasmus Ristolainen Jersey . Nikolaos Kounenakis has been hired as an assistant coach, the team announced on Monday. Jack Eichel Jersey . -- Each time the Utah Jazz threatened Memphis lead, the Grizzlies responded with defensive stops. SEATTLE -- Lloyd McClendon is always looking for a little pop to come from his designated hitter when he sets up the Seattle Mariners lineup. Yes, even when Endy Chavez is the DH. "How about Endy?" McClendon said. "That was a pretty good swing." Chavez homered for the first time in more than a year and Seattles bullpen was again stellar behind starter Chris Young in the Mariners 3-2 win over the Cleveland Indians on Friday night. Chavez singled and scored in the first inning, then ended the night for Cleveland starter Trevor Bauer with a solo home run into the right-field seats with one out in the seventh. It was Chavezs first homer since May 30, 2013, at San Diego, a span of 265 plate appearances. "It feels great, especially in a tight game," Chavez said. "Im glad to hit a home run in that situation and put us in a better situation to win the game." Kyle Seager had two hits, including an RBI single, to continue his hot hitting at home. Brad Miller also added an RBI single as Seattle won for the sixth time in seven games. Seager is hitting .613 in his past eight home games, but McClendon continues to be unsatisfied and expecting more from his third baseman. "Hes getting better," McClendon said with a smirk. Fernando Rodney worked the ninth for his 22nd save although it was bumpy. Nick Swisher singled and scored on Michael Bourns two-out single, but Rodney got Asdrubal Cabrera to pop up for the final out. Rodney was the last of five Seattle relievers that allowed three hits and struck out four after Young was lifted. Young (7-4) was done after five innings despite giving up just four hits and one run. The Indians made him work deep into counts and his pitch count was at 91 after five innings. "They made me work and I wasnt as sharp as I wanted to be and I was probably a little lucky tonight. They hit some balls hard right at guys," Young said. "The bullpen came in and did a phenomenal job. Those guys pickked me up.dddddddddddd" Joe Beimel tossed a perfect sixth and Danny Farquhar was solid in the seventh, although the Indians missed a chance to keep the inning alive because of a poor baserunning decision. With two outs, first baseman Logan Morrison booted Bourns grounder with Swisher on first. Swisher never stopped at second, but Morrison recovered and threw him out at third. Cleveland threatened again in the eighth on a two-out walk by Carlos Santana and a double from Jason Kipnis. Charlie Furbush got Lonnie Chisenhall to ground out, ending the inning. "The bullpen has been outstanding. Theyve been unbelievable. You just have complete confidence in all of them," Young said. "Tonight is a perfect example why. They came in, got 12 big outs and we won." Chavez led off the first with an infield single and stole second base with two outs. Seager then dumped a single into centre and Chavez was able to score standing up. The Mariners scored in almost the same way in the fourth. Michael Saunders singled with two outs and advanced to second on a wild pitch before Miller looped a base hit to centre for a 2-1 lead. Chavez provided some cushion with the 29th homer of his career. It was the third straight start in which Bauer (2-4) pitched into the seventh, but he has not finished that inning this season. He threw 111 pitches, below his season high of 119, and gave up nine hits while striking out five. "Early he fought his command a little bit, he didnt work ahead very often," Cleveland manager Terry Francona said. "But as he got into the game, I thought he got much better." NOTES: Seattles bullpen has allowed two earned runs in the past 24 innings. ... Cleveland plans to start LHP T.J. House in Sundays series finale. House still must be recalled from the minors. ... The Indians hope RHP Justin Masterson, scratched from Sundays start with a sore knee, will be able to go Tuesday in Los Angeles against the Dodgers. 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